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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP98161.1Cysteine desulfurase; Pfam:pfam00266 Aminotransferase class-V. (384 aa)    
Predicted Functional Partners:
AMP99440.1
Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
 0.982
AMQ01356.1
Hypothetical protein; Pfam:pfam00899 ThiF family.
   
 0.974
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
  
 
0.918
AMP99957.1
Cysteine desulfurase; Pfam:pfam00266 Aminotransferase class-V.
  
  
 
0.907
AMP98160.1
MBL fold metallo-hydrolase; Pfam:pfam00753 Metallo-beta-lactamase superfamily.
   
 
 0.698
AMP99476.1
Pfam:pfam00211 Adenylate and Guanylate cyclase catalytic domain.
  
 0.671
AMP97073.1
Ferredoxin; Pfam:pfam00111 2Fe-2S iron-sulfur cluster binding domain.
  
 0.662
AMQ01235.1
Ferredoxin.
  
 0.662
AMP97110.1
Molecular chaperone Hsc20; Pfam:pfam00226 DnaJ domain.
  
 
 0.648
AMQ01184.1
Pfam:pfam02082 Transcriptional regulator.
 
  
 0.620
Your Current Organism:
Pedobacter cryoconitis
NCBI taxonomy Id: 188932
Other names: DSM 14825, LMG 21415, LMG:21415, P. cryoconitis, Pedobacter cryoconitis Margesin et al. 2003
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