node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMP97032.1 | AMP97763.1 | AY601_0059 | AY601_0822 | Riboflavin synthase alpha subunit; Pfam:pfam00677 Lumazine binding domain. | Pfam:pfam13419 Haloacid dehalogenase-like hydrolase. | 0.901 |
AMP97032.1 | AMP98338.1 | AY601_0059 | AY601_1421 | Riboflavin synthase alpha subunit; Pfam:pfam00677 Lumazine binding domain. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
AMP97032.1 | AMQ01674.1 | AY601_0059 | AY601_4853 | Riboflavin synthase alpha subunit; Pfam:pfam00677 Lumazine binding domain. | Riboflavin biosynthesis protein RibF; Pfam:pfam06574 FAD synthetase; Belongs to the ribF family. | 0.928 |
AMP97032.1 | ribB | AY601_0059 | AY601_3168 | Riboflavin synthase alpha subunit; Pfam:pfam00677 Lumazine binding domain. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.993 |
AMP97032.1 | ribBA | AY601_0059 | AY601_4838 | Riboflavin synthase alpha subunit; Pfam:pfam00677 Lumazine binding domain. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
AMP97032.1 | ribH | AY601_0059 | AY601_3680 | Riboflavin synthase alpha subunit; Pfam:pfam00677 Lumazine binding domain. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
AMP97763.1 | AMP97032.1 | AY601_0822 | AY601_0059 | Pfam:pfam13419 Haloacid dehalogenase-like hydrolase. | Riboflavin synthase alpha subunit; Pfam:pfam00677 Lumazine binding domain. | 0.901 |
AMP97763.1 | AMP98338.1 | AY601_0822 | AY601_1421 | Pfam:pfam13419 Haloacid dehalogenase-like hydrolase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.921 |
AMP97763.1 | AMQ01674.1 | AY601_0822 | AY601_4853 | Pfam:pfam13419 Haloacid dehalogenase-like hydrolase. | Riboflavin biosynthesis protein RibF; Pfam:pfam06574 FAD synthetase; Belongs to the ribF family. | 0.908 |
AMP97763.1 | ribH | AY601_0822 | AY601_3680 | Pfam:pfam13419 Haloacid dehalogenase-like hydrolase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.902 |
AMP98338.1 | AMP97032.1 | AY601_1421 | AY601_0059 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase alpha subunit; Pfam:pfam00677 Lumazine binding domain. | 0.999 |
AMP98338.1 | AMP97763.1 | AY601_1421 | AY601_0822 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Pfam:pfam13419 Haloacid dehalogenase-like hydrolase. | 0.921 |
AMP98338.1 | AMP99969.1 | AY601_1421 | AY601_3096 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nitrogen utilization protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.665 |
AMP98338.1 | AMQ01674.1 | AY601_1421 | AY601_4853 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin biosynthesis protein RibF; Pfam:pfam06574 FAD synthetase; Belongs to the ribF family. | 0.655 |
AMP98338.1 | guaB | AY601_1421 | AY601_2530 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.694 |
AMP98338.1 | metK | AY601_1421 | AY601_4431 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.574 |
AMP98338.1 | ribB | AY601_1421 | AY601_3168 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.989 |
AMP98338.1 | ribBA | AY601_1421 | AY601_4838 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
AMP98338.1 | ribH | AY601_1421 | AY601_3680 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.995 |
AMP99969.1 | AMP98338.1 | AY601_3096 | AY601_1421 | Nitrogen utilization protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.665 |