close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftrFormylmethanofuran-tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. (297 aa)    
Predicted Functional Partners:
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family.
 
 
 0.997
fwdA
Formylmethanofuran dehydrogenase, subunit A.
 
 
 0.990
fmdA-2
Formylmethanofuran dehydrogenase, subunit A.
 
 
 0.990
fae-hps
D-arabino 3-hexulose 6-phosphate formaldehyde lyase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
 
  
 0.984
fmdA
Formylmethanofuran dehydrogenase, subunit A.
 
 
 0.982
fwdB-2
Formylmethanofuran dehydrogenase, subunit B.
 
 
 0.979
MA_3006
Formaldehyde-activating enzyme.
  
  
 0.977
fwdB
Formylmethanofuran dehydrogenase, subunit B.
 
 
 0.976
fmdB-2
Formylmethanofuran dehydrogenase, subunit B.
 
 
 0.974
fmdB
Formylmethanofuran dehydrogenase, subunit B.
 
 
 0.972
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.