Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fdhDFormate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family. (241 aa)    
Predicted Functional Partners:
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
  
 0.833
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
 
 
 0.817
moaC
Molybdenum cofactor biosynthesis protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
   
 0.728
cooF
Carbon-monoxide dehydrogenase, Fe-S subunit.
 
   
 0.678
cooC-2
CODH nickel-insertion accessory protein.
      
 0.625
cooC-3
CODH nickel-insertion accessory protein.
      
 0.625
cooC
Carbon-monoxide dehydrogenase accessory protein.
  
   
 0.590
metF
5,10-methylenetetrahydrofolate reductase (FADH).
     
 0.573
mobB
Molybdopterin synthase catalytic subunit; Molybdopterin-guanine dinucleotide biosynthesis protein B/molybdopterin converting factor, large subunit.
 
   
 0.569
fmdE
Formylmethanofuran dehydrogenase, subunit E.
     
 0.566
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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