Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_0345Conserved hypothetical protein. (131 aa)    
Predicted Functional Partners:
MA_0344
MotA/TolQ/ExbB proton channel family protein.
 
    0.941
MA_0343
Conserved hypothetical protein.
 
     0.872
MA_0346
Protoporphyrin IX magnesium chelatase.
 
    0.856
MA_4426
MotA/TolQ/ExbB proton channel family protein.
 
    0.844
MA_4641
MotA/TolQ/ExbB proton channel family protein.
 
    0.819
MA_0348
Protoporphyrin IX magnesium chelatase.
 
    0.744
MA_4424
Hypothetical protein.
 
    0.735
cobN
Cobalamin biosynthesis protein N.
 
    0.726
MA_4643
Hypothetical protein.
 
    0.718
MA_0385
Hypothetical protein (multi-domain).
 
    0.715
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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