Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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pcm-1protein-L-isoaspartate (D-aspartate) O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity). (251 aa)    
Predicted Functional Partners:
MA_0545
Conserved hypothetical protein.
       0.810
fpoC
F(420)H(2) dehydrogenase, subunit FpoC.
  
   0.775
fpoA
F(420)H(2) dehydrogenase, subunit FpoA.
  
   0.754
fpoD
F(420)H(2) dehydrogenase, subunit FpoD.
  
   0.725
fpoN
F(420)H(2) dehydrogenase, subunit FpoN.
  
   0.724
surE
Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
 0.653
fpoB
F(420)H(2) dehydrogenase, subunit FpoB; Belongs to the complex I 20 kDa subunit family.
  
   0.644
fpoH
F(420)H(2) dehydrogenase, subunit FpoH; Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2):heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples th [...]
  
   0.643
fpoM
F(420)H(2) dehydrogenase, subunit FpoM.
  
   0.624
fpoI
F(420)H(2) dehydrogenase, subunit FpoI.
  
   0.590
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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