Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MA_0551Sensory transduction histidine kinase. (1349 aa)    
Predicted Functional Partners:
MA_1469
Response regulator receiver.
 
     0.711
MA_1468
Response regulator receiver.
 
     0.699
MA_2445
Response regulator receiver.
 
   
 0.588
MA_2561
Conserved hypothetical protein.
  
     0.518
msrB
Pilin-like transcription factor; Belongs to the MsrB Met sulfoxide reductase family.
     
 0.515
msrA
protein-methionine-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.514
cmtA
methylcobalamin:CoM methyltransferase isozyme A.
     
 0.514
MA_0459
Conserved hypothetical protein.
      
 0.513
MA_0864
Hypothetical protein.
  
     0.493
MA_2397
Sensory transduction histidine kinase.
 
   
0.471
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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