Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_0586Conserved hypothetical protein. (101 aa)    
Predicted Functional Partners:
hpcE
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase.
       0.947
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
 
     0.768
MA_4428
Conserved hypothetical protein.
  
     0.717
MA_0591
Conserved hypothetical protein.
  
     0.714
MA_3019
Conserved hypothetical protein.
  
     0.712
MA_0818
Conserved hypothetical protein.
  
     0.700
MA_3018
Conserved hypothetical protein.
  
     0.699
rpl44e
Ribosomal protein L44e; Binds to the 23S rRNA.
  
     0.693
MA_1736
Mov34 family protein.
  
     0.671
MA_4000
Conserved hypothetical protein.
  
     0.671
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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