Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
trmM1-methylguanosine tRNA methyltransferase. (336 aa)    
Predicted Functional Partners:
dph5
Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
 
  
 0.831
MA_0611
Conserved hypothetical protein.
 
     0.819
tfb
Archaeal transcription factor B; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
 
     0.810
rfcL
Replication factor C, large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily.
 
    0.767
hat
Histone acetyltransferase.
 
  
 0.722
hel308
Helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
 
     0.696
MA_0609
RNA-binding protein; Involved in rRNA processing.
  
  
 0.694
rpoA2
DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
  
 0.666
MA_0893
Conserved hypothetical protein.
 
    0.663
ef1B
Translation elongation factor 1, subunit beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
 
   
 0.641
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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