Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
eif2ATranslation initiation factor 2, subunit alpha. (271 aa)    
Predicted Functional Partners:
nop10
Conserved hypothetical protein; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
 
  
 0.996
eif5
Translation initiation factor 5; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family.
  
 0.995
rps3
Ribosomal protein S3p; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
  
 0.993
rps3ae
Ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 0.993
eif2G
Translation initiation factor 2, subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
  
 0.993
rps10
Ribosomal protein S10p; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
 
 0.991
rps6e
Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 0.989
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
   
 0.988
rps19
Ribosomal protein S19p; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
  
 0.986
rps24e
Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
  
 0.986
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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