Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_0680Conserved hypothetical protein. (96 aa)    
Predicted Functional Partners:
MA_0679
Predicted protein.
       0.923
MA_0678
Conserved hypothetical protein.
 
     0.922
MA_0682
SpoU rRNA methylase.
       0.811
MA_0893
Conserved hypothetical protein.
 
     0.769
mcm2
Mcm2 DNA replication licensing factor; Belongs to the MCM family.
 
     0.753
eif5
Translation initiation factor 5; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family.
 
     0.741
MA_3869
Conserved hypothetical protein.
 
     0.732
MA_0591
Conserved hypothetical protein.
 
     0.710
MA_1279
Conserved hypothetical protein.
 
     0.706
ribK
Conserved hypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.703
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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