Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MA_0799Conserved hypothetical protein. (320 aa)    
Predicted Functional Partners:
MA_0798
N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein.
 
  
 0.840
MA_0797
Polysaccharide deacetylase.
  
  
 0.808
MA_4440
Polysaccharide deacetylase.
 
  
 0.686
nadK
Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.617
hypE
Hydrogenase expression/formation protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.615
MA_4078
Hypothetical protein (multi-domain).
 
  
 0.584
MA_2838
Conserved hypothetical protein.
 
     0.547
MA_0796
Predicted protein.
  
    0.521
thiD
Phosphomethylpyrimidine kinase.
  
    0.460
MA_0260
Predicted protein.
  
     0.456
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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