Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
fwdAFormylmethanofuran dehydrogenase, subunit A. (575 aa)    
Predicted Functional Partners:
fwdC
Formylmethanofuran dehydrogenase, subunit C.
 
  0.998
fwdB
Formylmethanofuran dehydrogenase, subunit B.
 
 0.998
ftr
Formylmethanofuran-tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
 
 0.988
fwuD
Formylmethanofuran dehydrogenase, subunit D.
 
 
 0.973
fmdC
Formylmethanofuran dehydrogenase, subunit C.
 
   0.936
fmdC-2
Formylmethanofuran dehydrogenase, subunit C.
 
   0.936
fmdB-2
Formylmethanofuran dehydrogenase, subunit B.
 
 
 0.932
fmdB
Formylmethanofuran dehydrogenase, subunit B.
 
 
 0.927
fmdB-3
Formylmethanofuran dehydrogenase, subunit B.
 
 
 0.927
fwdB-2
Formylmethanofuran dehydrogenase, subunit B.
 
 
 0.923
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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