Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_0909Conserved hypothetical protein. (640 aa)    
Predicted Functional Partners:
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
       0.702
flaI-2
Flagella accessory protein I.
 
   
 0.699
flaI
Flagella accessory protein I.
 
   
 0.697
flaH-2
Flagella accessory protein H.
  
   
 0.677
flaH
Flagella accessory protein H.
  
   
 0.674
flaJ-2
Flagella accessory protein J.
  
   
 0.664
flaJ
Flagella accessory protein J.
  
   
 0.656
leuS
leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
     0.649
MA_4415
3-isopropylmalate dehydratase.
  
   
 0.620
MA_4505
Conserved hypothetical protein.
 
   
 0.618
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
Server load: low (12%) [HD]