Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MA_0920Conserved hypothetical protein. (180 aa)    
Predicted Functional Partners:
MA_2518
RIO1/ZK632.3/MJ0444 family protein.
   
 0.999
MA_0894
Conserved hypothetical protein.
   
 0.986
ksgA
Dimethyladenosine rRNA methyltransferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
  
 
 0.957
rps8
Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
    
 0.955
rps4
Ribosomal protein S4p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 0.950
rps6e
Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 
 0.950
rps11
Ribosomal protein S11p; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
   
 0.949
rps28e
Ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
  
 
 0.948
rps3ae
Ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
   
 0.944
rps17e
Ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.
   
 0.944
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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