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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mttB-2Trimethylamine methyltransferase; Catalyzes the transfer of a methyl group from trimethylamine to the corrinoid cofactor of MttC. (495 aa)    
Predicted Functional Partners:
mttC-2
Trimethylamine corrinoid protein; Acts probably as a methyl group carrier between MttB and either MtbA or MtaA.
 
 
 0.987
MA_4364
Corrinoid protein.
 
 
 0.965
mtbA
methylcobalamin:CoM methyltransferase isozyme A; Methyltransferase involved in methanogenesis from methylamines methanol pathway. Catalyzes the transfer of the methyl group from the methylated corrinoid protein MtmC (MtmC1 or MtmC2) to coenzyme M, forming the substrate for coenzyme-B sulfoethylthiotransferase (By similarity); Belongs to the uroporphyrinogen decarboxylase family. MtbA/MtaA subfamily.
 
  
 0.960
mttC
Trimethylamine corrinoid protein; Acts probably as a methyl group carrier between MttB and either MtbA or MtaA.
 
 
 0.956
MA_4164
Corrinoid protein.
 
 
 0.954
mtbB
Dimethylamine methyltransferase; Catalyzes the transfer of a methyl group from dimethylamine to the corrinoid cofactor of MtbC.
    
 0.925
mtbB-2
Dimethylamine methyltransferase; Catalyzes the transfer of a methyl group from dimethylamine to the corrinoid cofactor of MtbC.
    
 0.925
mtbB-3
Dimethylamine methyltransferase; Catalyzes the transfer of a methyl group from dimethylamine to the corrinoid cofactor of MtbC.
    
 0.925
mttB
Trimethylamine methyltransferase; Catalyzes the transfer of a methyl group from trimethylamine to the corrinoid cofactor of MttC.
  
  
 
0.900
mtbC
Dimethylamine corrinoid protein; Acts as a methyl group carrier between MtbB and MtbA. Belongs to the methylamine corrinoid protein family.
 
 
 0.890
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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