Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cobYNucleoside triphosphate (NTP):5-deoxyadenosylcobinamide phosphate nucleotidyltransferase. (203 aa)    
Predicted Functional Partners:
cobS
Cobalamin (5-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.996
cobD
Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
  0.985
MA_0940
Conserved hypothetical protein.
 
     0.964
hisC-2
Histidinol-phosphate aminotransferase.
 
     0.900
MA_0935
Predicted protein.
       0.837
MA_3887
Conserved hypothetical protein; Belongs to the UPF0284 family.
 
     0.790
sufC
ABC transporter, ATP-binding protein.
       0.663
MA_3997
Conserved hypothetical protein; Belongs to the UPF0288 family.
  
     0.663
MA_0936
Conserved hypothetical protein.
       0.657
MA_3993
Conserved hypothetical protein.
  
     0.650
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
Server load: low (16%) [HD]