Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_0989Transcriptional regulator, MerR family. (284 aa)    
Predicted Functional Partners:
rpoB1
DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.468
rpoB2
DNA-directed RNA polymerase, subunit B; Belongs to the RNA polymerase beta chain family.
   
   0.468
rpoK
DNA-directed RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
    
   0.451
MA_0108
Glyoxalase.
 
     0.441
rpoA2
DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.435
rpoA1
DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.435
MA_2942
Transposase.
  
     0.427
MA_0988
Predicted protein.
       0.426
MA_3502
Transposase.
  
     0.421
MA_2074
Transposase.
  
     0.419
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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