Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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erf1-2Peptide chain release factor, subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (415 aa)    
Predicted Functional Partners:
eif5
Translation initiation factor 5; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family.
  
  
 0.968
MA_3204
RNase L inhibitor.
  
 
 0.967
ef1A
Translation elongation factor 1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
  
 0.947
rpl15e
Ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 0.943
rps3ae
Ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 0.928
rps15
Ribosomal protein S15p.
 
 0.926
rps4e
Ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family.
  
  0.922
rpl19e
Ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
  
  0.921
rpl24
Ribosomal protein L24p; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
  0.920
rpl32e
Ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family.
  
  0.918
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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