cdhC protein (Methanosarcina acetivorans) - STRING interaction network

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cdhC

Carbon-monoxide dehydrogenase, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex). (469 aa)

Predicted Functional Partners:

cdhE

0.999

cdhD

0.999

cdhA

0.999

cdhD-2

0.999

cdhB

0.998

cdhA-2

0.997

cdhB-2

0.996

cdhA-3

0.996

cdhE-2

0.988

cooC

0.969

Your Current Organism:

Methanosarcina acetivorans

NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cdhA	cdhA-2	MA_1016	MA_3860	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	0.901
cdhA	cdhA-3	MA_1016	MA_4399	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	0.901
cdhA	cdhB	MA_1016	MA_1015	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit epsilon; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD- mediated CO oxidation.	0.999
cdhA	cdhB-2	MA_1016	MA_3861	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit epsilon; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD- mediated CO oxidation.	0.999
cdhA	cdhC	MA_1016	MA_1014	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex).	0.999
cdhA	cdhD	MA_1016	MA_1012	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit delta; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex (By similarity).	0.996
cdhA	cdhD-2	MA_1016	MA_3864	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit delta; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex (By similarity).	0.983
cdhA	cdhE	MA_1016	MA_1011	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit gamma; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.	0.997
cdhA	cdhE-2	MA_1016	MA_3865	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit gamma.	0.956
cdhA	cooC	MA_1016	MA_1013	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase accessory protein.	0.836
cdhA-2	cdhA	MA_3860	MA_1016	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	0.901
cdhA-2	cdhA-3	MA_3860	MA_4399	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	0.900
cdhA-2	cdhB	MA_3860	MA_1015	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit epsilon; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD- mediated CO oxidation.	0.999
cdhA-2	cdhB-2	MA_3860	MA_3861	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit epsilon; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD- mediated CO oxidation.	0.999
cdhA-2	cdhC	MA_3860	MA_1014	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex).	0.997
cdhA-2	cdhD	MA_3860	MA_1012	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit delta; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex (By similarity).	0.983
cdhA-2	cdhD-2	MA_3860	MA_3864	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit delta; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex (By similarity).	0.996
cdhA-2	cdhE	MA_3860	MA_1011	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit gamma; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.	0.996
cdhA-2	cdhE-2	MA_3860	MA_3865	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase, subunit gamma.	0.967
cdhA-2	cooC	MA_3860	MA_1013	Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Carbon-monoxide dehydrogenase accessory protein.	0.693

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