Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MA_1273ABC transporter, ATP-binding protein. (355 aa)    
Predicted Functional Partners:
MA_1272
Conserved hypothetical protein.
 
  
 0.986
MA_1271
Predicted protein.
 
   
 0.947
MA_1228
Conserved hypothetical protein.
 
  
 0.943
MA_1229
Predicted protein.
 
     0.755
hypB
Hydrogenase expression/formation protein.
  
  
 0.680
MA_2839
ABC transporter, permease protein.
 
 
 0.472
comDE
Sulfopyruvate decarboxylase; Involved in the biosynthesis of the coenzyme M (2- mercaptoethanesulfonic acid). Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde. Is not able to decarboxylate the analogous compounds 2-oxoglutarate or 2-oxosuberate.
 
     0.448
thrC-2
Threonine synthase; Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate. Does not display threonine synthase activity like the paralog protein ThrC.
 
     0.409
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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