Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MA_1389Holocytochrome-c synthase. (225 aa)    
Predicted Functional Partners:
ccmC
Heme exporter protein C.
  
  
 0.582
MA_3365
Predicted protein.
 
    0.544
MA_3750
Predicted protein.
  
     0.475
MA_1069
Conserved hypothetical protein.
 
    0.472
MA_0207
Predicted protein.
 
   
 0.460
MA_0387
Conserved hypothetical protein.
  
    0.459
MA_2881
GufA protein.
  
    0.459
murD
UDP-N-acetylmuramoylalanine-D-glutamate ligase; Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the activation the g-propionate side chain of 15,17(3)-seco-F430-17(3)-acid (seco-F430) for intramolecular C-C bond formation to yield the carbocyclic F ring of coenzyme F430. Belongs to the MurCDEF family.
 
    0.456
MA_3958
Conserved hypothetical protein.
  
     0.444
MA_0068
Hypothetical protein (multi-domain).
 
     0.439
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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