Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fpoOF(420)H(2) dehydrogenase, subunit FpoO. (120 aa)    
Predicted Functional Partners:
fpoJ-2
F(420)H(2) dehydrogenase, subunit FpoJ.
       0.943
fpoK
F(420)H(2) dehydrogenase, subunit FpoK.
       0.943
fpoL
F(420)H(2) dehydrogenase, subunit FpoL.
       0.943
fpoM
F(420)H(2) dehydrogenase, subunit FpoM.
       0.943
fpoN
F(420)H(2) dehydrogenase, subunit FpoN.
       0.943
fpoJ
F(420)H(2) dehydrogenase, subunit FpoJ.
       0.942
fpoH
F(420)H(2) dehydrogenase, subunit FpoH; Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2):heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples th [...]
       0.941
fpoI
F(420)H(2) dehydrogenase, subunit FpoI.
       0.941
fpoD
F(420)H(2) dehydrogenase, subunit FpoD.
       0.937
fpoC
F(420)H(2) dehydrogenase, subunit FpoC.
       0.932
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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