Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_1656Hypothetical protein (multi-domain). (373 aa)    
Predicted Functional Partners:
MA_4554
SUA5/yciO/yrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
       0.611
MA_2004
FtsJ-like methyltransferase.
     
 0.592
MA_1569
Pap2 superfamily protein.
 
   
 0.477
MA_4172
Hypothetical protein (multi-domain).
  
     0.444
MA_1106
Gliding motility protein.
 
 
 0.439
rad50
Purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
 
     0.439
MA_0563
Conserved hypothetical protein.
 
   
 0.437
MA_1430
Hypothetical protein.
 
 
 0.428
MA_0868
Multidrug ABC transporter, ATP-binding protein.
 
 
 0.426
MA_3259
Serine/threonine specific protein phosphatase.
 
    0.422
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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