STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MA_1735Malate dehydrogenase (oxaloacetate decarboxylating). (390 aa)    
Predicted Functional Partners:
fumB
Fumarate hydratase, subunit beta.
 
 0.982
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 
 0.955
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.943
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.943
fumA
Fumarate hydratase, subunit alpha.
 
 
 0.939
pycA
Pyruvate carboxylase subunit A.
  
 0.930
pycB
Pyruvate carboxylase subunit B.
    
 0.917
MA_3075
2-oxoacid ferredoxin oxidoreductase, subunit alpha.
  
 
 0.917
porA
Pyruvate synthase, subunit alpha.
  
 
 0.916
porB
Pyruvate synthase, subunit beta.
    
 0.914
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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