Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
radCDNA repair protein; Belongs to the UPF0758 family. (229 aa)    
Predicted Functional Partners:
MA_0748
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
 
  
 0.895
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.818
moaB
Molybdenum cofactor biosynthesis protein B.
     
 0.786
MA_1713
Predicted protein.
      
 0.782
MA_1981
Conserved hypothetical protein.
       0.750
ior
Indolepyruvate ferredoxin oxidoreductase, subunit alpha; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
       0.738
mobB
Molybdopterin synthase catalytic subunit; Molybdopterin-guanine dinucleotide biosynthesis protein B/molybdopterin converting factor, large subunit.
       0.703
uvrD
DNA helicase.
     
 0.695
rps3
Ribosomal protein S3p; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
      
 0.636
dcd
dCTP deaminase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
     
 0.634
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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