STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepOEndothelin converting enzyme-like protein PepO. (665 aa)    
Predicted Functional Partners:
pepN
Membrane alanine aminopeptidase.
     
 0.532
MA_2629
Triacylglycerol lipase.
 
 
 0.459
fen
FlaP endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...]
  
  
 0.437
gap
Glyceraldehyde 3-phosphate dehydrogenase (phosphorylating).
  
  
 0.418
gap-2
Glyceraldehyde 3-phosphate dehydrogenase (phosphorylating).
  
  
 0.418
MA_2246
Squamous cell carcinoma antigen; Belongs to the serpin family.
    
 0.406
MA_2612
Serine proteinase inhibitor.
    
 0.406
MA_2613
Serine proteinase inhibitor; Belongs to the serpin family.
    
 0.406
MA_3388
Serine protease inhibitor; Belongs to the serpin family.
    
 0.406
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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