Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
blaBeta-lactamase. (227 aa)    
Predicted Functional Partners:
ndh
NADH dehydrogenase.
 
 
 0.768
groES
groES protein (Cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
   
 
 0.700
MA_1794
Metallo-beta-lactamase.
 
 
 0.692
MA_2320
Metallo-beta-lactamase.
 
 
 0.668
truA
Pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
   
 
 0.614
arsC
Arsenate reductase.
  
 
 0.585
MA_0746
Conserved hypothetical protein.
  
 
 0.557
MA_2500
Hypothetical protein (multi-domain).
  
 
 0.557
MA_3178
Rhodanese family protein.
  
 
 0.557
MA_0491
Bacterial extracellular solute-binding family 3 protein.
 
  
 0.549
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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