Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_2105StySKI methylase. (104 aa)    
Predicted Functional Partners:
MA_2106
Hypothetical protein (multi-domain).
  
 
 0.874
MA_2116
Site-specific DNA-methyltransferase (adenine-specific), subunit M.
 
 
 0.847
MA_0485
Hypothetical protein; Contains a restriction-modification enzyme domain.
 
 
 0.841
hsdM
Site-specific DNA-methyltransferase (adenine-specific), subunit M.
  
 
 0.791
MA_2451
Hypothetical protein.
 
  
 0.648
MA_3581
Type I site-specific deoxyribonuclease.
 
  
 0.628
MA_2122
Type I site-specific deoxyribonuclease.
 
 
 0.621
MA_2678
Predicted protein.
 
 
 0.613
MA_2119
Hypothetical protein (multi-domain).
 
  
 0.514
hsdR
Type I site-specific deoxyribonuclease protein R.
  
 
 0.495
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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