Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_2120Type I site-specific deoxyribonuclease. (487 aa)    
Predicted Functional Partners:
MA_2116
Site-specific DNA-methyltransferase (adenine-specific), subunit M.
 
 
 0.976
MA_0485
Hypothetical protein; Contains a restriction-modification enzyme domain.
 
 
 0.950
MA_2122
Type I site-specific deoxyribonuclease.
 
 
 0.925
MA_2678
Predicted protein.
 
 
 0.872
MA_2118
Conserved hypothetical protein.
  
 
 0.870
hsdM
Site-specific DNA-methyltransferase (adenine-specific), subunit M.
 
 
 0.837
MA_2119
Hypothetical protein (multi-domain).
  
  
 0.810
MA_2117
Predicted protein.
       0.649
MA_2451
Hypothetical protein.
  
  
 0.644
MA_3581
Type I site-specific deoxyribonuclease.
  
  
 0.644
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
Server load: low (8%) [HD]