Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_2212Conserved hypothetical protein. (124 aa)    
Predicted Functional Partners:
MA_3151
Conserved hypothetical protein.
  
     0.703
MA_1835
Conserved hypothetical protein.
  
     0.665
MA_2055
MarR family protein.
     
 0.616
MA_4541
Mrr restriction system protein.
  
    0.579
comDE
Sulfopyruvate decarboxylase; Involved in the biosynthesis of the coenzyme M (2- mercaptoethanesulfonic acid). Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde. Is not able to decarboxylate the analogous compounds 2-oxoglutarate or 2-oxosuberate.
  
    0.540
MA_3130
Conserved hypothetical protein.
      
 0.516
MA_3302
Conserved hypothetical protein.
      
 0.516
MA_2211
Transcription repressor.
       0.507
MA_2963
Iron-sulfur cluster binding protein.
   
    0.434
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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