STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MA_2249Conserved hypothetical protein. (209 aa)    
Predicted Functional Partners:
mgl
Methionine gamma-lyase.
    
 0.811
metY
O-acetylhomoserine (thiol)-lyase.
    
 0.811
MA_1821
Conserved hypothetical protein.
    
  0.804
MA_0053
Conserved hypothetical protein.
    
  0.802
MA_0054
Conserved hypothetical protein.
    
  0.802
ahcY2
Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family.
    
  0.802
metE
5-methyltetrahydropteroyltriglutamate homocysteine S-methyltransferase.
    
  0.802
MA_1822
Iron-sulfur cluster binding protein.
     
  0.800
MA_2467
Conserved hypothetical protein.
  
     0.538
MA_2250
Predicted protein.
       0.515
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.