Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_2385Predicted protein. (73 aa)    
Predicted Functional Partners:
MA_0873
PQQ enzyme repeat domain protein.
  
 0.744
MA_0874
Predicted protein.
  
 0.744
MA_1519
WD-domain containing protein.
  
 0.744
MA_2525
WD40-repeat containing protein.
  
 0.741
MA_2580
WD-domain containing protein.
  
 0.741
MA_1381
GTP-binding protein.
   
 0.712
MA_2301
Hypothetical protein; Contains leucine-rich tandem repeats.
   
 0.712
MA_3869
Conserved hypothetical protein.
   
 
 0.692
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
   
 
 0.691
MA_0112
Archaeal transcription factor S; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
   
 
 0.658
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
Server load: medium (42%) [HD]