Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_2501Cation-transporting P-type ATPase. (947 aa)    
Predicted Functional Partners:
MA_3020
Conserved hypothetical protein.
  
 
 0.695
MA_2502
Conserved hypothetical protein.
  
    0.599
rps8
Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
   
 
 0.534
MA_1381
GTP-binding protein.
  
 0.530
MA_2301
Hypothetical protein; Contains leucine-rich tandem repeats.
  
 0.530
MA_0916
Erythrocyte band 7 integral membrane protein.
   
 0.524
MA_3330
Conserved hypothetical protein.
   
 
 0.524
MA_2309
Hypothetical protein (multi-domain).
  
 
 0.518
rps13
Ribosomal protein S13p; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family.
   
 
 0.517
MA_2500
Hypothetical protein (multi-domain).
     
 0.513
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
Server load: low (20%) [HD]