Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_2580WD-domain containing protein. (1051 aa)    
Predicted Functional Partners:
MA_3404
GTPase.
 
 0.850
MA_2888
Histone deacetylase.
  
 0.827
MA_0189
Helicase (SNF2 family).
 
 
 0.818
MA_1661
Peptidylprolyl isomerase.
  
 0.811
MA_1390
GTP-binding protein.
  
 
 0.787
eif6
Translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
 
 
 0.778
rpl30e
Ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family.
  
 
  0.777
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 0.775
alaXM
alanyl-tRNA synthetase domain protein; Functions in trans to edit the amino acid moiety from mischarged charged tRNA(Ala).
  
 0.775
rpl30
Ribosomal protein L30p.
  
 0.774
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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