Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fwdG-2Tungsten formylmethanofuran dehydrogenase, subunit G. (154 aa)    
Predicted Functional Partners:
fwuD
Formylmethanofuran dehydrogenase, subunit D.
 
 
 0.993
fwdD
Formylmethanofuran dehydrogenase.
 
 
 0.991
fwdB-2
Formylmethanofuran dehydrogenase, subunit B.
 
 
   0.980
MA_2867
Polyferredoxin.
 
  
 0.978
fmdD-2
Formylmethanofuran dehydrogenase, subunit D.
 
 
 0.964
fmdD
Formylmethanofuran dehydrogenase, subunit D.
 
 
 0.963
cdhB-2
Carbon-monoxide dehydrogenase, subunit epsilon; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD- mediated CO oxidation.
 
  
  0.915
cdhB
Carbon-monoxide dehydrogenase, subunit epsilon; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD- mediated CO oxidation.
 
  
  0.914
cdhA
Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
 
  
 0.912
cdhA-2
Carbon-monoxide dehydrogenase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
 
  
 0.911
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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