Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_2963Iron-sulfur cluster binding protein. (172 aa)    
Predicted Functional Partners:
MA_2962
Aldehyde ferredoxin oxidoreductase.
 
 
 0.993
MA_1714
Aldehyde ferredoxin oxidoreductase.
 
 
 0.919
MA_0167
Conserved hypothetical protein.
 
 
 0.905
vhtC
Cytochrome b.
  
 
 0.898
vhtC-2
Cytochrome b.
  
 
 0.898
MA_4541
Mrr restriction system protein.
  
    0.784
hdrA
Heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). Catalyzes the transfer of electrons from ferredoxin to CoM-S-S-CoB during methanogenesis from acetate. Electrons transfer from ferredoxin to CoM-S-S-CoB via HdrA2, HdrC2 and HdrB2. In addition, the complex can use electron bifurcation to direct electron pairs from reduced coenzyme F420 towards the reduction of both ferredoxin and CoB- CoM heterodisulfide. Th [...]
     
 0.757
cooF
Carbon-monoxide dehydrogenase, Fe-S subunit.
 
   
 0.748
MA_0685
Sulfite reductase.
   
 
 0.737
MA_3165
Hypothetical protein.
   
 
 0.737
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.