Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_3151Conserved hypothetical protein. (290 aa)    
Predicted Functional Partners:
MA_2212
Conserved hypothetical protein.
  
     0.703
MA_0359
Conserved hypothetical protein.
  
     0.700
MA_2207
Conserved hypothetical protein.
  
     0.697
MA_2057
Conserved hypothetical protein.
  
     0.683
MA_4622
Conserved hypothetical protein.
  
     0.650
cdc6-2
Cell division control protein 6, subunit A; Involved in regulation of DNA replication.
 
     0.545
comDE
Sulfopyruvate decarboxylase; Involved in the biosynthesis of the coenzyme M (2- mercaptoethanesulfonic acid). Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde. Is not able to decarboxylate the analogous compounds 2-oxoglutarate or 2-oxosuberate.
  
    0.540
MA_4541
Mrr restriction system protein.
   
    0.524
nac
Conserved hypothetical protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.518
pheA
Chorismate mutase/prephenate dehydratase.
     
 0.517
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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