gdhA protein (Methanosarcina acetivorans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

gdhA

Glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (374 aa)

Predicted Functional Partners:

glnA-2

0.977

glnA

0.971

gltD

0.957

MA_0249

0.952

argJ

0.928

MA_1385

0.924

aspB

0.924

MA_1949

0.922

nifK

0.918

nifD

0.917

Your Current Organism:

Methanosarcina acetivorans

NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MA_0249	MA_1385	MA_0249	MA_1385	Citrate (si)-synthase.	Aspartate aminotransferase.	0.839
MA_0249	aspB	MA_0249	MA_1819	Citrate (si)-synthase.	Aspartate aminotransferase.	0.839
MA_0249	gdhA	MA_0249	MA_3169	Citrate (si)-synthase.	Glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.952
MA_0249	gltD	MA_0249	MA_3787	Citrate (si)-synthase.	Glutamate synthase (NADPH).	0.853
MA_1385	MA_0249	MA_1385	MA_0249	Aspartate aminotransferase.	Citrate (si)-synthase.	0.839
MA_1385	MA_1949	MA_1385	MA_1949	Aspartate aminotransferase.	Glutamate decarboxylase.	0.832
MA_1385	argJ	MA_1385	MA_3564	Aspartate aminotransferase.	Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.	0.914
MA_1385	aspB	MA_1385	MA_1819	Aspartate aminotransferase.	Aspartate aminotransferase.	0.905
MA_1385	gdhA	MA_1385	MA_3169	Aspartate aminotransferase.	Glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.924
MA_1385	gltD	MA_1385	MA_3787	Aspartate aminotransferase.	Glutamate synthase (NADPH).	0.920
MA_1949	MA_1385	MA_1949	MA_1385	Glutamate decarboxylase.	Aspartate aminotransferase.	0.832
MA_1949	aspB	MA_1949	MA_1819	Glutamate decarboxylase.	Aspartate aminotransferase.	0.832
MA_1949	gdhA	MA_1949	MA_3169	Glutamate decarboxylase.	Glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.922
MA_1949	glnA	MA_1949	MA_3382	Glutamate decarboxylase.	Glutamate-ammonia ligase; Belongs to the glutamine synthetase family.	0.917
MA_1949	glnA-2	MA_1949	MA_4216	Glutamate decarboxylase.	Glutamate-ammonia ligase; Belongs to the glutamine synthetase family.	0.917
MA_1949	gltD	MA_1949	MA_3787	Glutamate decarboxylase.	Glutamate synthase (NADPH).	0.904
argJ	MA_1385	MA_3564	MA_1385	Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.	Aspartate aminotransferase.	0.914
argJ	aspB	MA_3564	MA_1819	Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.	Aspartate aminotransferase.	0.914
argJ	gdhA	MA_3564	MA_3169	Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.	Glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.928
aspB	MA_0249	MA_1819	MA_0249	Aspartate aminotransferase.	Citrate (si)-synthase.	0.839