Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_3243Integral membrane protein. (291 aa)    
Predicted Functional Partners:
MA_3108
Glutathione-regulated potassium-efflux system protein.
  
  
 0.783
kefC
Glutathione-regulated potassium-efflux system protein.
  
  
 0.783
MA_4255
C-type cytochrome biogenesis protein.
  
  
 0.770
MA_0422
Aldo/keto reductase.
  
    0.764
glnP
Glutamine ABC transporter, permease protein.
 
  
 0.607
cmtM-3
methylcobamide:CoM methyltransferase isozyme M.
 
  
 0.516
MA_2694
Conserved hypothetical protein.
  
  
 0.512
MA_1666
Integral membrane protein.
  
     0.511
adh-2
Alcohol dehydrogenase.
  
  
 0.499
MA_2881
GufA protein.
  
 
 0.474
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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