Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_3285Conserved hypothetical protein. (312 aa)    
Predicted Functional Partners:
MA_1162
Conserved hypothetical protein.
   
    0.827
MA_0422
Aldo/keto reductase.
   
    0.792
MA_4469
Conserved hypothetical protein.
  
    0.790
bioB
Biotin synthase; Catalyzes the isomerization of L-lysine to (2R,3R)-3- methylornithine via a radical-based mechanism (Probable). Is required for the biosynthesis of pyrrolysine; Belongs to the radical SAM superfamily. PylB family.
  
    0.773
MA_3108
Glutathione-regulated potassium-efflux system protein.
   
    0.764
kefC
Glutathione-regulated potassium-efflux system protein.
   
    0.764
MA_0114
Conserved hypothetical protein.
  
    0.576
hdrE
Heterodisulfide reductase, subunit E; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrE may be responsible for anchoring the complex to the membrane.
  
     0.572
MA_4466
CAAX amino terminal protease family protein.
  
    0.570
MA_2750
Predicted protein.
 
     0.567
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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