Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_3299Conserved hypothetical protein. (438 aa)    
Predicted Functional Partners:
MA_1822
Iron-sulfur cluster binding protein.
 
    0.812
MA_1715
Conserved hypothetical protein; Belongs to the UPF0280 family.
 
   
 0.801
comDE
Sulfopyruvate decarboxylase; Involved in the biosynthesis of the coenzyme M (2- mercaptoethanesulfonic acid). Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde. Is not able to decarboxylate the analogous compounds 2-oxoglutarate or 2-oxosuberate.
 
     0.648
thrC-2
Threonine synthase; Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate. Does not display threonine synthase activity like the paralog protein ThrC.
     
 0.634
MA_4640
Conserved hypothetical protein.
  
     0.504
MA_0343
Conserved hypothetical protein.
  
     0.495
MA_3856
Conserved hypothetical protein; Belongs to the UPF0285 family.
  
     0.472
MA_4427
Conserved hypothetical protein.
  
     0.471
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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