Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cysESerine O-acetyltransferase. (232 aa)    
Predicted Functional Partners:
cysK
Cysteine synthase.
 
 0.993
MA_2721
Hypothetical protein (multi-domain).
  
  
  0.942
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.913
MA_2737
Serine O-acetyltransferase.
  
  
 
0.903
serB
Phosphoserine phosphatase.
 
 
 0.867
MA_2572
Homoserine dehydrogenase.
    
 0.828
trpB
Tryptophan synthase, subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
 0.817
trpA
Tryptophan synthase, subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate; Belongs to the TrpA family.
    
 0.816
trpB-2
Tryptophan synthase, subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
 0.811
cysS
cysteinyl-tRNA synthetase.
  
  
 0.758
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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