Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_3446Conserved hypothetical protein. (360 aa)    
Predicted Functional Partners:
MA_4078
Hypothetical protein (multi-domain).
   
    0.754
MA_3471
Hypothetical protein (multi-domain).
     
 0.750
MA_0429
Conserved hypothetical protein; Belongs to the LarC family.
 
    0.571
MA_1031
Conserved hypothetical protein.
 
     0.509
MA_0628
Conserved hypothetical protein.
 
     0.499
fpoM
F(420)H(2) dehydrogenase, subunit FpoM.
  
    0.458
MA_0411
Predicted protein.
  
    0.448
adh-2
Alcohol dehydrogenase.
  
    0.441
MA_0412
Predicted protein.
  
    0.440
MA_0240
Conserved hypothetical protein.
 
    0.432
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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