Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
MA_3471Hypothetical protein (multi-domain). (4226 aa)    
Predicted Functional Partners:
gltD
Glutamate synthase (NADPH).
   
 
 0.988
cbiD
Cobalamin biosynthesis protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
     
 0.947
MA_3033
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 0.943
cysG
uroporphyrin-III C-methyltransferase.
  
  
 0.939
cobD
Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
     
 0.927
cbiH
precorrin-3B C17-methyltransferase.
     
 0.916
cbiF
Precorrin-4 C11-methyltransferase.
     
 0.916
MA_3887
Conserved hypothetical protein; Belongs to the UPF0284 family.
     
 0.913
MA_2084
cob(I)alamin adenosyltransferase.
     
 0.902
cbiC
precorrin-8X methylmutase.
     
 0.896
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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