Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MA_3544Conserved hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate. (226 aa)    
Predicted Functional Partners:
MA_2967
Haloacid dehalogenase-like hydrolase.
    
 0.913
radA-2
DNA repair protein; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
  
  
 0.909
MA_4631
D-lactate dehydrogenase.
    
 0.906
rbcL
Ribulose bisphosphate carboxylase, large subunit; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily.
    
 0.904
coaD
Cytidylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family.
 
   
 0.626
MA_1736
Mov34 family protein.
   
 
 0.480
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.447
MA_3287
PmbA/TldD family protein; Putative modulator of DNA gyrase.
 
     0.437
hypD
Hydrogenase expression/formation protein.
       0.436
MA_0451
Beta-phosphoglucomutase.
 
  
 0.405
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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