Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_3556Predicted protein. (868 aa)    
Predicted Functional Partners:
MA_3365
Predicted protein.
  
     0.747
MA_3146
Predicted protein.
  
     0.732
MA_3145
Predicted protein.
  
     0.726
hdrE
Heterodisulfide reductase, subunit E; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrE may be responsible for anchoring the complex to the membrane.
  
     0.724
MA_3958
Conserved hypothetical protein.
  
     0.716
MA_2845
Predicted protein.
  
     0.687
MA_0285
Hypothetical protein (multi-domain).
  
     0.657
MA_0284
Hypothetical protein (multi-domain).
  
     0.628
MA_3633
Predicted protein.
  
     0.618
MA_4432
Conserved hypothetical protein.
  
     0.614
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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