Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_3586Transcriptional regulator, TetR family. (214 aa)    
Predicted Functional Partners:
MA_2746
Conserved hypothetical protein.
  
     0.532
MA_2764
Transcriptional regulator, TetR family.
  
     0.471
MA_2761
Transcriptional regulator, TetR family.
  
     0.464
MA_2766
Transcriptional regulator, TetR family.
  
     0.464
MA_2771
Transcriptional regulator, MarR family.
 
   
 0.435
MA_2948
Transcriptional regulator, TetR family.
  
     0.426
MA_3189
Multidrug resistance operon repressor.
 
   
 0.426
MA_2206
Transcription repressor.
 
   
 0.423
MA_2055
MarR family protein.
 
   
 0.416
MA_2211
Transcription repressor.
 
   
 0.404
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
Server load: low (16%) [HD]