MA_3704 protein (Methanosarcina acetivorans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

MA_3704

TPR-domain containing protein. (1004 aa)

Predicted Functional Partners:

MA_0255

0.719

MA_1519

0.686

MA_3893

0.644

MA_1368

0.628

MA_0874

0.597

MA_2525

0.593

MA_0873

0.590

MA_2580

0.581

rpoK

0.568

ndk

0.563

Your Current Organism:

Methanosarcina acetivorans

NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MA_0255	MA_0873	MA_0255	MA_0873	4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF.	PQQ enzyme repeat domain protein.	0.683
MA_0255	MA_0874	MA_0255	MA_0874	4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF.	Predicted protein.	0.683
MA_0255	MA_1368	MA_0255	MA_1368	4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF.	Thioredoxin reductase (NADPH).	0.785
MA_0255	MA_1519	MA_0255	MA_1519	4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF.	WD-domain containing protein.	0.683
MA_0255	MA_2525	MA_0255	MA_2525	4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF.	WD40-repeat containing protein.	0.683
MA_0255	MA_2580	MA_0255	MA_2580	4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF.	WD-domain containing protein.	0.683
MA_0255	MA_3704	MA_0255	MA_3704	4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF.	TPR-domain containing protein.	0.719
MA_0255	MA_3893	MA_0255	MA_3893	4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF.	Conserved hypothetical protein.	0.450
MA_0873	MA_0255	MA_0873	MA_0255	PQQ enzyme repeat domain protein.	4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF.	0.683
MA_0873	MA_0874	MA_0873	MA_0874	PQQ enzyme repeat domain protein.	Predicted protein.	0.822
MA_0873	MA_3704	MA_0873	MA_3704	PQQ enzyme repeat domain protein.	TPR-domain containing protein.	0.590
MA_0873	MA_3893	MA_0873	MA_3893	PQQ enzyme repeat domain protein.	Conserved hypothetical protein.	0.469
MA_0873	ndk	MA_0873	MA_1524	PQQ enzyme repeat domain protein.	Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	0.701
MA_0873	rpoK	MA_0873	MA_0599	PQQ enzyme repeat domain protein.	DNA-directed RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.	0.496
MA_0874	MA_0255	MA_0874	MA_0255	Predicted protein.	4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF.	0.683
MA_0874	MA_0873	MA_0874	MA_0873	Predicted protein.	PQQ enzyme repeat domain protein.	0.822
MA_0874	MA_3704	MA_0874	MA_3704	Predicted protein.	TPR-domain containing protein.	0.597
MA_0874	MA_3893	MA_0874	MA_3893	Predicted protein.	Conserved hypothetical protein.	0.538
MA_0874	ndk	MA_0874	MA_1524	Predicted protein.	Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	0.701
MA_0874	rpoK	MA_0874	MA_0599	Predicted protein.	DNA-directed RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.	0.496