Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MA_3789Nitroreductase. (180 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.816
MA_3792
Acetolactate synthase, large subunit.
  
  
 0.774
MA_3791
Acetolactate synthase, small subunit.
       0.759
MA_0165
Conserved hypothetical protein.
  
  
 0.559
MA_0108
Glyoxalase.
  
  
 0.500
MA_1028
Long-chain fatty-acid-CoA ligase.
   
 
 0.484
MA_1422
Long-chain fatty-acid-CoA ligase.
   
 
 0.484
MA_3717
Long-chain fatty-acid-CoA ligase.
   
 
 0.484
leuA-2
2-isopropylmalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
 0.468
MA_0846
ABC-2 type transporter.
  
  
 0.454
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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